Isoforskolin is the principal active component of C. forskohlii, native to China. It functions as an anti-inflammatory agent by reducing the secretion of lipopolysaccharide (LPS)-induced cytokines, specifically TNF-α, IL-1β, IL-6, and IL-8, in human mononuclear leukocytes. It is used for the treatment of Lyme arthritis.
- Principal active component of C. forskohlii.
- Reduces LPS-induced cytokine secretion (TNF-α, IL-1β, IL-6, and IL-8).
- Acts as an anti-inflammatory agent.
- Potentially treats Lyme arthritis.